Causal relationship between telomere length and risk of intracranial aneurysm: a bidirectional Mendelian randomization study

Causal relationship between telomere length and risk of intracranial aneurysm: a bidirectional Mendelian randomization study

BackgroundTelomere length is closely linked to the aging phenotype, where cellular aging results in the production of a cascade of cell factors and the senescence-associated secretory phenotype (SASP), leading to an inflammatory response. The presence of inflammation plays a crucial role in the form...

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Bibliographic Details
Main Authors: Bangjie Xu, Jiangbin Ren, Siqi Zhu, Yu Ding, Wei Zhou, Qing Guo, Yan Fang, Jing Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Neurology
Subjects:
telomere length
intracranial aneurysm
Mendelian randomization
causality
single nucleotide polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1355895/full

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https://www.frontiersin.org/articles/10.3389/fneur.2024.1355895/full

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