Superiority of Droplet Digital PCR Over Real-Time Quantitative PCR for <i>JAK2</i> <i>V617F</i> Allele Mutational Burden Assessment in Myeloproliferative Neoplasms: A Retrospective Study

Superiority of Droplet Digital PCR Over Real-Time Quantitative PCR for <i>JAK2</i> <i>V617F</i> Allele Mutational Burden Assessment in Myeloproliferative Neoplasms: A Retrospective Study

<i>JAK2</i> <i>V617F</i> mutational status is an essential diagnostic index in myeloproliferative neoplasms (MPNs). Although widely used for detection of <i>JAK2 V617F</i> mutation in peripheral blood (PB), sensitive real-time quantitative PCR (qPCR) presents some...

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Bibliographic Details
Main Authors: Francesco La Rocca, Vitina Grieco, Vitalba Ruggieri, Emanuela Zifarone, Oreste Villani, Pietro Zoppoli, Sabino Russi, Simona Laurino, Geppino Falco, Giovanni Calice, Anna Marinaccio, Maria Iole Natalicchio, Francesco Albano, Pellegrino Musto
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Diagnostics
Subjects:
myeloproliferative neoplasms
qpcr
droplet digital pcr
<i>jak2</i>
Online Access:https://www.mdpi.com/2075-4418/10/3/143

Internet

https://www.mdpi.com/2075-4418/10/3/143

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