A Pore Forming Toxin-like Protein Derived from Chinese Red Belly Toad <i>Bombina maxima</i> Triggers the Pyroptosis of Hippomal Neural Cells and Impairs the Cognitive Ability of Mice

A Pore Forming Toxin-like Protein Derived from Chinese Red Belly Toad <i>Bombina maxima</i> Triggers the Pyroptosis of Hippomal Neural Cells and Impairs the Cognitive Ability of Mice

Toxin-like proteins and peptides of skin secretions from amphibians play important physiological and pathological roles in amphibians. βγ-CAT is a Chinese red-belly toad-derived pore-forming toxin-like protein complex that consists of aerolysin domain, crystalline domain, and trefoil factor domain a...

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Bibliographic Details
Main Authors: Qingqing Ye, Qiquan Wang, Wenhui Lee, Yang Xiang, Jixue Yuan, Yun Zhang, Xiaolong Guo
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Toxins
Subjects:
pore-forming toxin
red-belly toad
<i>Bombina maxima</i>
hippocampal neuronal cell
pyroptosis
cognitive function
Online Access:https://www.mdpi.com/2072-6651/15/3/191

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https://www.mdpi.com/2072-6651/15/3/191

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