Diagnosis of α-thalassaemia by colorimetric gap loop mediated isothermal amplification

Abstract α-Thalassaemia is an inherited haemoglobin disorder that results from the defective synthesis of α-globin protein. Couples whom both carry the α-thalassaemia 1 gene are at risk of having a foetus with the most severe thalassaemia, Hb Bart’s hydrops fetalis, with a risk of maternal mortality...

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Bibliographic Details
Main Authors: Worakawee Chumworathayee, Thongperm Munkongdee, Nattrika Buasuwan, Pornthip Chaichompoo, Saovaros Svasti
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36676-2