Clinical and pharmacological factors influencing serum clozapine and norclozapine levels

Clinical and pharmacological factors influencing serum clozapine and norclozapine levels

Background:Clozapine (CLO) is a very effective antipsychotic, whose use is associated with dose-dependent risk of complications. Due to high interindividual variability in CLO metabolism, there is a need to identify factors affecting the blood concentrations of CLO and its active metabolite, norcloz...

Full description

Bibliographic Details
Main Authors: Anna Mach, Anna Wnorowska, Marcin Siwek, Marcin Wojnar, Maria Radziwoń-Zaleska
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
clozapine
norclozapine
therapeutic levels
toxic levels
psychotropic drugs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1356813/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1356813/full

Similar Items