Chronomodulated drug delivery system of Irbesartan: Formulation and development using Desing of Experiment (DoE)
The work is based on pulsatile principles to deliver a programmed dose of Irbesartan, an angiotensin-II receptor antagonist for chronotherapy of hypertension induced by excessive secretion of aldosterone, thereby lower the blood pressure at early morning. Solid dispersion of Irbesartan, a BCS class...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Pharmacy, Cairo University
2018-06-01
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| Series: | Bulletin of Faculty of Pharmacy Cairo University |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110093117300649 |