Dynamic patterns of YAP1 expression and cellular localization in the developing and injured utricle

Abstract The Hippo signaling pathway is a key regulator of tissue development and regeneration. Activation of the Hippo pathway leads to nuclear translocation of the YAP1 transcriptional coactivator, resulting in changes in gene expression and cell cycle entry. Recent studies have demonstrated the n...

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Bibliographic Details
Main Authors: Vikrant Borse, Matthew Barton, Harry Arndt, Tejbeer Kaur, Mark E. Warchol
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77775-8