Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis

Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis

<p>Abstract</p> <p>Background</p> <p>Human ß-defensins are a family of antimicrobial peptides located at the mucosal surface. Both sequence multi-site variations (MSV) and copy-number variants (CNV) of the defensin-encoding genes are associated with increased risk for v...

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Bibliographic Details
Main Authors: Taudien Stefan, Gäbel Gabor, Kuss Oliver, Groth Marco, Grützmann Robert, Huse Klaus, Kluttig Alexander, Wolf Andreas, Nothnagel Michael, Rosenstiel Philip, Greiser Karin Halina, Werdan Karl, Krawczak Michael, Pilarsky Christian, Platzer Matthias
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Research Notes
Subjects:
Defensins
Single nucleotide variants
Copy number variation
Chronic pancreatitis
Pancreatic ductal adenocarcinoma
Online Access:http://www.biomedcentral.com/1756-0500/5/629

Internet

http://www.biomedcentral.com/1756-0500/5/629

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