Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trialResearch in context

Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trialResearch in context

Summary: Background: The utility of early metabolic response assessment to guide selection of the systemic component of definitive chemoradiotherapy (dCRT) for oesophageal cancer is uncertain. Methods: In this multi-centre, randomised, open-label, phase II substudy of the radiotherapy dose-escalati...

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Bibliographic Details
Main Authors: Somnath Mukherjee, Christopher N. Hurt, Richard Adams, Andrew Bateman, Kevin M. Bradley, Sarah Bridges, Stephen Falk, Gareth Griffiths, Sarah Gwynne, Christopher M. Jones, Philip J. Markham, Tim Maughan, Lisette S. Nixon, Ganesh Radhakrishna, Rajarshi Roy, Simon Schoenbuchner, Hamid Sheikh, Emiliano Spezi, Maria Hawkins, Thomas D.L. Crosby
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:EClinicalMedicine
Subjects:
Oesophageal squamous cell carcinoma
Oesophageal adenocarcinoma
Chemoradiotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023002365

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http://www.sciencedirect.com/science/article/pii/S2589537023002365

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