A Chemically Defined TLR3 Agonist with Anticancer Activity

A Chemically Defined TLR3 Agonist with Anticancer Activity

ABSTRACTToll-like receptor 3 (TLR3) agonists such as polyinosinic:polycytidylic acid (poly(I:C)) have immunostimulatory effects that can be taken advantage of to induce anticancer immune responses in preclinical models. In addition, poly(I:C) has been introduced into clinical trials to demonstrate i...

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Bibliographic Details
Main Authors: Julie Le Naour, Sylvain Thierry, Sarah Adriana Scuderi, Mathilde Boucard-Jourdin, Peng Liu, Marc Bonnin, Yuhong Pan, Clémence Perret, Liwei Zhao, Misha Mao, Chloé Renoux, María Pérez-Lanzón, Baptiste Martin, Oliver Kepp, Guido Kroemer, Bettina Werlé
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Cancer immunotherapy
dendritic cells
formyl peptide receptor 1
immmunogenic cell death
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2227510

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2023.2227510

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