Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs

Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs

Atherosclerosis is the main cause of cardio-cerebrovascular diseases. Endothelial-mesenchymal transition plays an important role in atherosclerosis. Icariin has a protective effect on atherosclerosis; however, the underlying mechanism remains unclear. In this study, we explored the molecular mechani...

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Bibliographic Details
Main Authors: Shan Liu, Dong-sheng Xu, Min Li, Yang Zhang, Qi Li, Teng-teng Li, Li-qun Ren
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
atherosclerosis
endothelial-to-mesenchymal transition
H19
miR-148b-3p
ELF5
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303784

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http://www.sciencedirect.com/science/article/pii/S2162253120303784

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