Executable network of SARS-CoV-2-host interaction predicts drug combination treatments

Abstract The COVID-19 pandemic has pushed healthcare systems globally to a breaking point. The urgent need for effective and affordable COVID-19 treatments calls for repurposing combinations of approved drugs. The challenge is to identify which combinations are likely to be most effective and at wha...

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Bibliographic Details
Main Authors: Rowan Howell, Matthew A. Clarke, Ann-Kathrin Reuschl, Tianyi Chen, Sean Abbott-Imboden, Mervyn Singer, David M. Lowe, Clare L. Bennett, Benjamin Chain, Clare Jolly, Jasmin Fisher
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-022-00561-5