Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease

Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease

IntroductionChronic kidney disease (CKD) presents a critical global health challenge, marked by the progressive decline of renal function. This study explores the role of the 3β-hydroxysteroid dehydrogenase type 2 enzyme (HSD3B2) and the steroid hormone biosynthesis pathway in CKD pathogenesis and p...

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Bibliographic Details
Main Authors: Yiyi Zuo, Dongqing Zha, Yue Zhang, Wan Yang, Jie Jiang, Kangning Wang, Runze Zhang, Ziyi Chen, Qing He
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Endocrinology
Subjects:
chronic kidney disease
metabolomics
HSD3B2
steroid hormone biosynthesis
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1358124/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1358124/full

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