Molecular mechanism of ferroptosis and its role in the occurrence and treatment of diabetes

Ferroptosis is an iron-dependent programmed cell death, which is different from apoptosis, necrosis, and autophagy. Specifically, under the action of divalent iron or ester oxygenase, unsaturated fatty acids that are highly expressed on the cell membrane are catalyzed to produce lipid peroxidation,...

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Bibliographic Details
Main Authors: Guanghui Du, Qi Zhang, Xiaobo Huang, Yi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1018829/full