The effects of Leishmania RNA virus 2 (LRV2) on the virulence factors of L. major and pro-inflammatory biomarkers: an in vitro study on human monocyte cell line (THP-1)

The effects of Leishmania RNA virus 2 (LRV2) on the virulence factors of L. major and pro-inflammatory biomarkers: an in vitro study on human monocyte cell line (THP-1)

Abstract Background Cutaneous Leishmaniasis (CL) is a parasitic disease with diverse outcomes. Clinical diversity is influenced by various factors such as Leishmania species and host genetic background. The role of Leishmania RNA virus (LRV), as an endosymbiont, is suggested to not only affect the p...

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Main Authors: Zahra Mirabedini, Hamed Mirjalali, Elham Kazemirad, Ali Khamesipour, Katayoun Samimirad, Mona Koosha, Reza Saberi, Hanieh Mohammad Rahimi, Mehdi Mohebali, Homa Hajjaran
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Microbiology
Subjects:
Leishmania major
Leishmania RNA virus 2
Virulence factors
Pro-inflammatory biomarkers
In vitro
Online Access:https://doi.org/10.1186/s12866-023-03140-0

Internet

https://doi.org/10.1186/s12866-023-03140-0

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