Comparative Pharmacokinetic Study Among 3 Metformin Formulations in Healthy Mexican Volunteers: A Single-Dose, Randomized, Open-Label, 3-Period Crossover Study

Comparative Pharmacokinetic Study Among 3 Metformin Formulations in Healthy Mexican Volunteers: A Single-Dose, Randomized, Open-Label, 3-Period Crossover Study

Background: Type 2 diabetes mellitus is the most common form of diabetes. Metformin is a first-line drug for its treatment. In Mexico, there are 34 generic formulations of metformin, so brand-generic substitutions and generic-generic substitutions are a common practice. Generic products are compared...

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Bibliographic Details
Main Authors: Sandra Lucía Montoya-Eguía, DrC, Lourdes Garza-Ocañas, DrMed, Christian Tadeo Badillo-Castañeda, DrC, Eduardo Tamez-de la O, DrC, Teresa Zanatta-Calderón, DrC, Marco Vinicio Gómez-Meza, PhD, Humberto Garza-Ulloa, MC
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Current Therapeutic Research
Subjects:
Bioequivalence
generic formulations
metformin
Mexican population
pharmacokinetic
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X1400023X

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http://www.sciencedirect.com/science/article/pii/S0011393X1400023X

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