A HYPOTHETICAL ROLE FOR PLAGUE IN THE SELECTION OF MEFV MUTATION CARRIERS IN THE MEDITERRANEAN AREA
Familial Mediterranean fever (FMF) is the most common autoinflammatory disease associated with mutations in the MEFV gene encoding Pyrin. MEFV mutations are frequent in the Mediterranean region. Increased resistance to an infection endemic to this area could have caused a selective advantage for ind...
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| Format: | Article |
| Language: | English |
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South Kazakhstan Medical Academy
2020-08-01
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| Series: | Central Asian Journal of Medical Hypotheses and Ethics |
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| Online Access: | https://cajmhe.com/index.php/journal/article/view/7 |