Precursor-Directed Biosynthesis of Aminofulvenes: New Chalanilines from Endophytic Fungus <i>Chalara</i> sp.

Precursor-Directed Biosynthesis of Aminofulvenes: New Chalanilines from Endophytic Fungus <i>Chalara</i> sp.

The plant endophyte <i>Chalara</i> sp. is able to biotransform the epigenetic modifier vorinostat to form unique, aniline-containing polyketides named chalanilines. Here, we sought to expand the chemical diversity of chalaniline A-type molecules by changing the aniline moiety in the prec...

Full description

Bibliographic Details
Main Authors: Mahsa Khoshbakht, Jason Srey, Donovon A. Adpressa, Annika Jagels, Sandra Loesgen
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
precursor-directed biosynthesis
fungal metabolite
aminofulvenes
biotransformation
Online Access:https://www.mdpi.com/1420-3049/26/15/4418

Internet

https://www.mdpi.com/1420-3049/26/15/4418

Similar Items