Poly(ADP-Ribose) Polymerase Inhibitor PJ34 Reduces Brain Damage after Stroke in the Neonatal Mouse Brain

Poly(ADP-Ribose) Polymerase Inhibitor PJ34 Reduces Brain Damage after Stroke in the Neonatal Mouse Brain

The poly(ADP-ribose) polymerase inhibitor PJ34 has recently been reported to increase cerebral blood flow, via the endothelial NO synthase, in the naive mouse brain throughout life. We addressed here the benefits of PJ34 after neonatal ischemia on hemodynamics and components of the neurovascular uni...

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Bibliographic Details
Main Authors: Philippe Bonnin, Tania Vitalis, Leslie Schwendimann, Alexandre Boutigny, Nassim Mohamedi, Valérie C Besson, Christiane Charriaut-Marlangue
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Current Issues in Molecular Biology
Subjects:
neonatal ischemia
doppler ultrasonography
collateral circulation
blood-brain barrier
somatostatin receptor
octreotide
Online Access:https://www.mdpi.com/1467-3045/43/1/25

Internet

https://www.mdpi.com/1467-3045/43/1/25

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