Extra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton.

Extra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton.

Progesterone plays a role in breast cancer development and progression but the effects on breast cancer cell movement or invasion have not been fully explored. In this study, we investigate the actions of natural progesterone and of the synthetic progestin medroxyprogesterone acetate (MPA) on actin...

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Bibliographic Details
Main Authors: Xiao-Dong Fu, Maria S Giretti, Chiara Baldacci, Silvia Garibaldi, Marina Flamini, Angel Matias Sanchez, Angiolo Gadducci, Andrea R Genazzani, Tommaso Simoncini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2464736?pdf=render

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http://europepmc.org/articles/PMC2464736?pdf=render

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