A Comparative Study on Cyclodextrin Derivatives in Improving Oral Bioavailability of Etoricoxib as a Model Drug: Formulation and Evaluation of Solid Dispersion-Based Fast-Dissolving Tablets

A Comparative Study on Cyclodextrin Derivatives in Improving Oral Bioavailability of Etoricoxib as a Model Drug: Formulation and Evaluation of Solid Dispersion-Based Fast-Dissolving Tablets

Etoricoxib, as a model drug, has a poor solubility and dissolution rate. Cyclodextrin derivatives can be used to solve such a problem. A comparative study was run on three cyclodextrin derivatives, namely β-CD, HP β-CD, and SBE β-CD, to solve the drug problem through the formulation of solid dispers...

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Bibliographic Details
Main Authors: Doaa Elsegaie, Mohamed A. El-Nabarawi, Hanaa Abdelmonem Mahmoud, Mahmoud Teaima, Dina Louis
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
etoricoxib
solid dispersion
factorial design
carrier
Prosolv ODT<sup>®</sup>
F-melt type C<sup>®</sup>
Online Access:https://www.mdpi.com/2227-9059/11/9/2440

Internet

https://www.mdpi.com/2227-9059/11/9/2440

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