Destruxin A inhibits the hemocytin-mediated hemolymph immunity of host insects to facilitate Metarhizium infection

Summary: Insects have an effective innate immune system to protect themselves against fungal invasion. Metarhizium employs a toxin-based strategy using a nonribosomal peptide called destruxin A (DA) to counteract the host immune response. However, the mechanism by which DA inhibits insect immunity i...

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Bibliographic Details
Main Authors: Jingjing Wang, Hongwang Hu, Suyun Pang, Xuyu Yin, Bihao Cao, Jilei Huang, Xiaoli Xu, Qunfang Weng, Qiongbo Hu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000147