Common and distinct patterns of acquired uniparental disomy and homozygous deletions between lung squamous cell carcinomas and lung adenocarcinoma

Common and distinct patterns of acquired uniparental disomy and homozygous deletions between lung squamous cell carcinomas and lung adenocarcinoma

Acquired uniparental disomy (aUPD) is a chromosomal alteration that can lead to homozygosity of existing aberrations. We used data from The Cancer Genome Atlas SNP-based arrays to identify distinct and common aUPD profiles in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC). Moreov...

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Bibliographic Details
Main Authors: Musaffe Tuna, Gordon B Mills, Christopher I Amos
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Lung squamous cell carcinoma
Lung adenocarcinoma
Acquired uniparental disomy
Homozygous deletions
Genomics
Survival
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558623000568

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http://www.sciencedirect.com/science/article/pii/S1476558623000568

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