Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.

Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.

Tetracycline or doxycycline (dox)-regulated control of genetic elements allows inducible, reversible and tissue specific regulation of gene expression in mice. This approach provides a means to investigate protein function in specific cell lineages and at defined periods of development and disease....

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Bibliographic Details
Main Authors: Lukas E Dow, Zeina Nasr, Michael Saborowski, Saya H Ebbesen, Eusebio Manchado, Nilgun Tasdemir, Teresa Lee, Jerry Pelletier, Scott W Lowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990578?pdf=render

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http://europepmc.org/articles/PMC3990578?pdf=render

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