Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway

Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway

Abstract Background Muscle wasting, resulting from aging or pathological conditions, leads to reduced quality of life, increased morbidity, and increased mortality. Much research effort has been focused on the development of exercise mimetics to prevent muscle atrophy and weakness. In this study, we...

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Bibliographic Details
Main Authors: Hyebeen Kim, Sung Chun Cho, Hyeon‐Ju Jeong, Hye‐Young Lee, Myong‐Ho Jeong, Jung‐Hoon Pyun, Dongryeol Ryu, MinSeok Kim, Young‐Sam Lee, Minseok S. Kim, Sang Chul Park, Yun‐Il Lee, Jong‐Sun Kang
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Exercise mimetic
Hypertrophic response
Indoprofen
Muscle wasting
Muscle weakness
PDK1
Online Access:https://doi.org/10.1002/jcsm.12558

Internet

https://doi.org/10.1002/jcsm.12558

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