Comprehensive and Integrative Analysis of Two Novel SARS-CoV-2 Entry Associated Proteases CTSB and CTSL in Healthy Individuals and Cancer Patients

Comprehensive and Integrative Analysis of Two Novel SARS-CoV-2 Entry Associated Proteases CTSB and CTSL in Healthy Individuals and Cancer Patients

More than 200 million people have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and 4 million deaths have been reported worldwide to date. Cathepsin B/cathepsin L (CTSB/L) are SARS-CoV-2 entry–associated proteases and facilitate SARS-CoV-2 to infect host cells. Howe...

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Bibliographic Details
Main Authors: Yongbiao Huang, Shiyu Li, Shanshan Huang, Jingyao Tu, Xinyi Chen, Lingyan Xiao, Bo Liu, Xianglin Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
SARS-CoV-2
CTSB
CTSL
cancer
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.780751/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.780751/full

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