Protective Effect of Neurotrophic Agent T-817MA Against Inner Ear Barotrauma in the Guinea Pig

Abstract.: T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}azetidin-3-ol maleate), a neurotrophic compound newly synthesized for the treatment of Alzheimer’s disease, has been found to reduce oxidative stress and exert neuroprotective effects. By assessing the auditory functioning and observing...

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Bibliographic Details
Main Authors: Hitoshi Maekawa, Takeshi Matsunobu, Yasushi Satoh, Takaomi Kurioka, Asako Nakamura, Noboru Iwakami, Akihiro Shiotani
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306620