Complex interplay between autophagy and oxidative stress in the development of pulmonary disease

Complex interplay between autophagy and oxidative stress in the development of pulmonary disease

The autophagic pathway involves the encapsulation of substrates in double-membraned vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and recycling of metabolic precursors. Autophagy is a major cellular defense against oxidative stress, or related conditions that c...

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Bibliographic Details
Main Authors: Wojciech Ornatowski, Qing Lu, Manivannan Yegambaram, Alejandro E. Garcia, Evgeny A. Zemskov, Emin Maltepe, Jeffrey R. Fineman, Ting Wang, Stephen M. Black
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
Autophagy
Reactive oxygen species
Mitophagy
Oxidative stress
Mitochondria
Pulmonary disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308843

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http://www.sciencedirect.com/science/article/pii/S2213231720308843

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