Anti-ADAMTS13 Autoantibodies: From Pathophysiology to Prognostic Impact—A Review for Clinicians

Anti-ADAMTS13 Autoantibodies: From Pathophysiology to Prognostic Impact—A Review for Clinicians

Thrombotic thrombocytopenic purpura (TTP) is a fatal disease in which platelet-rich microthrombi cause end-organ ischemia and damage. TTP is caused by markedly reduced ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) activity. ADAMTS13 autoantibodies (auto...

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Bibliographic Details
Main Authors: Cristina Dainese, Federica Valeri, Benedetto Bruno, Alessandra Borchiellini
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Clinical Medicine
Subjects:
thrombotic thrombocytopenic purpura
Moskowitz syndrome
ADAMTS13 autoantibodies
ADAMTS13 inhibitors
Online Access:https://www.mdpi.com/2077-0383/12/17/5630

Internet

https://www.mdpi.com/2077-0383/12/17/5630

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