Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells

Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells

Abstract Background Vascular disease is a common and often severe complication in diabetes mellitus. Hyperglycemia and hypertension are considered to be two of the leading risk factors for vascular complications in diabetic patients. However, few pharmacologic agents could provide a combinational th...

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Bibliographic Details
Main Authors: Yu-Guang Ma, Jun-Wei Wang, Yun-Gang Bai, Mei Liu, Man-Jiang Xie, Zhi-Jun Dai
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Salidroside
Contractile activity
Vascular smooth muscle cells (VSMCs)
L-type Ca2+ channel (CaL)
Online Access:http://link.springer.com/article/10.1186/s40360-017-0135-8

Internet

http://link.springer.com/article/10.1186/s40360-017-0135-8

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