Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5

Abstract JmjC (Jumonji-C) domain-containing 5 (JMJD5) plays important roles in circadian regulation in plants and humans and is involved in embryonic development and cell proliferation. JMJD5 is a 2-oxoglutarate (2OG) and Fe(II) dependent oxygenase of the JmjC subfamily, which includes histone Nε-me...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Md. Saiful Islam, Marios Markoulides, Rasheduzzaman Chowdhury, Christopher J. Schofield
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2022-11-01
श्रृंखला:Scientific Reports
ऑनलाइन पहुंच:https://doi.org/10.1038/s41598-022-24154-0