Complement Inhibition for Geographic Atrophy: A Tempting Target with Mixed Results

Complement Inhibition for Geographic Atrophy: A Tempting Target with Mixed Results

Age-related macular degeneration (AMD) is a leading cause of blindness in older adults. One of the strongest genetic risk factors for AMD is a complement factor H (CFH) gene polymorphism characterized by a tyrosine-histidine change at amino acid position 402 (Y402H). The magnitude of this associatio...

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Bibliographic Details
Main Authors: Jonathan B. Lin, Omar A. Halawa, Joan W. Miller, Demetrios G. Vavvas
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
age-related macular degeneration
geographic atrophy
complement
retina
drusen
Online Access:https://www.mdpi.com/2077-0383/10/13/2890

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https://www.mdpi.com/2077-0383/10/13/2890

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