Multiplexed Strain Phenotyping Defines Consequences of Genetic Diversity in Mycobacterium tuberculosis for Infection and Vaccination Outcomes

Multiplexed Strain Phenotyping Defines Consequences of Genetic Diversity in Mycobacterium tuberculosis for Infection and Vaccination Outcomes

ABSTRACT There is growing evidence that genetic diversity in Mycobacterium tuberculosis, the causative agent of tuberculosis, contributes to the outcomes of infection and public health interventions, such as vaccination. Epidemiological studies suggest that among the phylogeographic lineages of M. t...

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Bibliographic Details
Main Authors: Allison F. Carey, Xin Wang, Nico Cicchetti, Caitlin N. Spaulding, Qingyun Liu, Forrest Hopkins, Jessica Brown, Jaimie Sixsmith, Rujapak Sutiwisesak, Samuel M. Behar, Thomas R. Ioerger, Sarah M. Fortune
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mSystems
Subjects:
BCG
TnSeq
clinical strains
genomics
mycobacterium
tuberculosis
Online Access:https://journals.asm.org/doi/10.1128/msystems.00110-22

Internet

https://journals.asm.org/doi/10.1128/msystems.00110-22

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