Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers

Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers

Abstract Background Chronic hepatitis B virus (HBV) infection is characterized by the presence of dysfunctional exhausted CD8+ T cells that hamper viral control. We investigated the phenotypic heterogeneity of exhausted CD8+ T cells in HBV carriers. Methods We enrolled 31 HBV carriers and 23 healthy...

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Bibliographic Details
Main Authors: Daixi Jiang, Can Chen, Danying Yan, Xiaobao Zhang, Xiaoxiao Liu, Dong Yan, Dawei Cui, Shigui Yang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Immunology
Subjects:
HBV
CD8+ T cell
CXCR5
Exhaustion
Flow cytometry
Online Access:https://doi.org/10.1186/s12865-022-00488-2

Internet

https://doi.org/10.1186/s12865-022-00488-2

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