Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle

Abstract Background Whole-genome sequencing and imputation methodologies have enabled the study of the effects of genomic variants with low to very low minor allele frequency (MAF) on variation in complex traits. Our objective was to estimate the proportion of variance explained by imputed sequence...

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Bibliographic Details
Main Authors: Qianqian Zhang, Mario P. L. Calus, Bernt Guldbrandtsen, Mogens Sandø Lund, Goutam Sahana
Format: Article
Language:deu
Published: BMC 2017-08-01
Series:Genetics Selection Evolution
Online Access:http://link.springer.com/article/10.1186/s12711-017-0336-z