PEDF-Mediated Mitophagy Triggers the Visual Cycle by Enhancing Mitochondrial Functions in a H<sub>2</sub>O<sub>2</sub>-Injured Rat Model
Retinal degenerative diseases result from oxidative stress and mitochondrial dysfunction, leading to the loss of visual acuity. Damaged retinal pigment epithelial (RPE) and photoreceptor cells undergo mitophagy. Pigment epithelium-derived factor (PEDF) protects from oxidative stress in RPE and impro...
| Main Authors: | , , , , , |
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| Format: | Article |
| Sprog: | English |
| Udgivet: |
MDPI AG
2021-05-01
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| Serier: | Cells |
| Fag: | |
| Online adgang: | https://www.mdpi.com/2073-4409/10/5/1117 |