Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

The nuclear envelope (NE) assembles and grows from bilayer lipids produced at the endoplasmic reticulum (ER). How ER membrane incorporation coordinates with assembly of nuclear pore complexes (NPCs) to generate a functional NE is not well understood. Here, we use the stereotypical first division of...

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Bibliographic Details
Main Authors: Michael Sean Mauro, Gunta Celma, Vitaly Zimyanin, Magdalena M Magaj, Kimberley H Gibson, Stefanie Redemann, Shirin Bahmanyar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
NDC1
nuclear pore complex
lipid synthesis
nuclear envelope
Nup107-160 complex
C. elegans embryos
Online Access:https://elifesciences.org/articles/75513

Internet

https://elifesciences.org/articles/75513

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