Chronic infection by atypical Toxoplasma gondii strain induces disturbance in microglia population and altered behaviour in mice

Chronic infection by atypical Toxoplasma gondii strain induces disturbance in microglia population and altered behaviour in mice

Toxoplasma gondii chronic infection is characterized by the establishment of tissue cysts in the brain and increased levels of IFN-γ, which can lead to brain circuitry interference and consequently abnormal behaviour in mice. In this sense, the study presented here sought to investigate the impact o...

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Bibliographic Details
Main Authors: Ramayana Morais de Medeiros Brito, Maria Carolina Machado da Silva, Flaviane Vieira-Santos, Camila de Almeida Lopes, Jorge Lucas Nascimento Souza, Alexandre Lazoski Bastilho, Heliana de Barros Fernandes, Aline Silva de Miranda, Antônio Carlos Pinheiro de Oliveira, Ricardo Wagner de Almeida Vitor, Valter Ferreira de Andrade-Neto, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Luísa Mourão Dias Magalhães
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Neuroinflammation
Toxoplasma gondii
Depression
Anxiety
Microglia depletion
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354623000662

Internet

http://www.sciencedirect.com/science/article/pii/S2666354623000662

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