Acute renal and neurotoxicity due to weight-based dosing of intravenous acyclovir: How to dose in obese patients?
Background: Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing. Inconsistency in clinical guideline recommendations and a lack of clear recommendations in the Summary...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-10-01
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| Series: | Clinical Infection in Practice |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590170220300339 |