Genetic Risk of Coronary Artery Disease, Features of Atherosclerosis, and Coronary Plaque Burden

Genetic Risk of Coronary Artery Disease, Features of Atherosclerosis, and Coronary Plaque Burden

Background Polygenic risk scores (PRSs) based on risk variants from genome‐wide association studies predict coronary artery disease (CAD) risk. However, it is unknown whether the PRS is associated with specific CAD characteristics. Methods and Results We consecutively included 1645 patients with sus...

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Bibliographic Details
Main Authors: Morten Krogh Christiansen, Louise Nissen, Simon Winther, Peter Loof Møller, Lars Frost, Jane Kirk Johansen, Henrik Kjærulf Jensen, Daníel Guðbjartsson, Hilma Holm, Kári Stefánsson, Hans Erik Bøtker, Morten Bøttcher, Mette Nyegaard
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
coronary artery disease
coronary computed tomography angiography
plaque
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.014795

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.014795

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