The effect of colchicine on cholesterol crystal formation, expansion and morphology: a potential mechanism in atherosclerosis

BackgroundInflammation is pivotal to the progression of atherosclerosis. Cholesterol crystals (CCs) that grow and enlarge within the plaque core can cause plaque rupture and trigger inflammation as they deposit into the atherosclerotic bed. Thus, agents that affect CC formation, expansion, and morph...

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Bibliographic Details
Main Authors: Zain Ul Abideen, Dorothy R. Pathak, Rand Sabanci, Megan Manu, George S. Abela
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1345521/full