Loss of synaptic ribbons is an early cause in ROS-induced acquired sensorineural hearing loss

Considerable evidence of reactive oxygen species (ROS) involvement in cochlear hair cell (HC) loss, leading to acquired sensorineural hearing loss (SNHL), were reported. Cochlear synaptopathy between HCs and spiral ganglion neurons has been gathering attention as a cochlear HC loss precursor not det...

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Bibliographic Details
Main Authors: Shunkou Kurasawa, Hiroaki Mohri, Keiji Tabuchi, Takehiko Ueyama
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123002954