3D printed multi-drug-loaded suppositories for acute severe ulcerative colitis

3D printed multi-drug-loaded suppositories for acute severe ulcerative colitis

Acute severe ulcerative colitis (ASUC) is a growing health burden that often requires treatment with multiple therapeutic agents. As inflammation is localised in the rectum and colon, local drug delivery using suppositories could improve therapeutic outcomes. Three-dimensional (3D) printing is a nov...

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Bibliographic Details
Main Authors: Atheer Awad, Eleanor Hollis, Alvaro Goyanes, Mine Orlu, Simon Gaisford, Abdul W. Basit
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Inflammatory bowel disease
Rectal corticosteroids
Janus kinase (JAK) inhibitors
Extrusion-assisted three-dimensional printing of drug products
Pressure-assisted micro syringe
Additive manufacturing of pharmaceuticals and medicines
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156723000099

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http://www.sciencedirect.com/science/article/pii/S2590156723000099

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