Explaining variability in early stages of [18F]‐flortaucipir tau‐PET binding: Focus on sex differences

Explaining variability in early stages of [18F]‐flortaucipir tau‐PET binding: Focus on sex differences

Abstract INTRODUCTION Female sex is associated with increased [18F]‐flortaucipir signal, which may be affected by amyloid pathology, age, and off‐target binding in skull and meninges. METHODS In this cross‐sectional study comprising 52 females and 52 matched males, we examined sex‐related difference...

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Bibliographic Details
Main Authors: Dario Bachmann, Andreas Buchmann, Sandro Studer, Antje Saake, Katrin Rauen, Esmeralda Gruber, Roger M. Nitsch, Christoph Hock, Anton Gietl, Valerie Treyer
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
age at menopause
Alzheimer's disease
amyloid pathology
hormone replacement therapy
off‐target binding
tau pathology
Online Access:https://doi.org/10.1002/dad2.12565

Internet

https://doi.org/10.1002/dad2.12565

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