Linear interaction between replication and transcription shapes DNA break dynamics at recurrent DNA break Clusters

Linear interaction between replication and transcription shapes DNA break dynamics at recurrent DNA break Clusters

Abstract Recurrent DNA break clusters (RDCs) are replication-transcription collision hotspots; many are unique to neural progenitor cells. Through high-resolution replication sequencing and a capture-ligation assay in mouse neural progenitor cells experiencing replication stress, we unravel the repl...

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Bibliographic Details
Main Authors: Lorenzo Corazzi, Vivien S. Ionasz, Sergej Andrejev, Li-Chin Wang, Athanasios Vouzas, Marco Giaisi, Giulia Di Muzio, Boyu Ding, Anna J. M. Marx, Jonas Henkenjohann, Michael M. Allers, David M. Gilbert, Pei-Chi Wei
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47934-w

Internet

https://doi.org/10.1038/s41467-024-47934-w

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