Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness

Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness

Abstract Background & Aims To clarify the biological roles, circularization process and secretion pathway of circRHOBTB3 in colorectal cancer (CRC) progression. Methods We performed a comprehensive analysis of circRNA levels in serum exosomes from multiple types of cancer patients in public data...

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Bibliographic Details
Main Authors: Chaoyi Chen, Hongfei Yu, Fengyan Han, Xuan Lai, Kehong Ye, Siqin Lei, Minglang Mai, Maode Lai, Honghe Zhang
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Molecular Cancer
Subjects:
Exosome
Metastasis
Colorectal cancer
circRHOBTB3
Circularization
Online Access:https://doi.org/10.1186/s12943-022-01511-1

Internet

https://doi.org/10.1186/s12943-022-01511-1

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