Trifluoroethanol Promoted Castagnoli–Cushman Cycloadditions of Imines with Homophthalic Anhydride

Lactams are essential compounds in medicinal chemistry and key intermediates in the synthesis of natural products. The Castagnoli–Cushman reaction (CCR) of homophthalic anhydride with imines is an exciting method for accessing cyclic densely substituted lactam products. Most CCRs need to be catalyze...

ver descrição completa

Detalhes bibliográficos
Main Authors: Thibault Bayles, Catherine Guillou
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2022-01-01
Colecção:Molecules
Assuntos:
Acesso em linha:https://www.mdpi.com/1420-3049/27/3/844