Trifluoroethanol Promoted Castagnoli–Cushman Cycloadditions of Imines with Homophthalic Anhydride

Trifluoroethanol Promoted Castagnoli–Cushman Cycloadditions of Imines with Homophthalic Anhydride

Lactams are essential compounds in medicinal chemistry and key intermediates in the synthesis of natural products. The Castagnoli–Cushman reaction (CCR) of homophthalic anhydride with imines is an exciting method for accessing cyclic densely substituted lactam products. Most CCRs need to be catalyze...

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Bibliographic Details
Main Authors:	Thibault Bayles, Catherine Guillou
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	Molecules
Subjects:	Castagnoli–Cushman reaction homophthalic anhydride imines lactam trifluoroethanol
Online Access:	https://www.mdpi.com/1420-3049/27/3/844

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