Emerging antioxidant therapies in Friedreich’s ataxia

Friedreich’s ataxia (FRDA) is a rare childhood neurologic disorder, affecting 1 in 50,000 Caucasians. The disease is caused by the abnormal expansion of the GAA repeat sequence in intron 1 of the FXN gene, leading to the reduced expression of the mitochondrial protein frataxin. The disease is charac...

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Bibliographic Details
Main Authors: Fred Jonathan Edzeamey, Zenouska Ramchunder, Charareh Pourzand, Sara Anjomani Virmouni
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1359618/full