Early treatment with noninvasive positive pressure ventilation prolongs survival in Amyotrophic Lateral Sclerosis patients with nocturnal respiratory insufficiency

<p>Abstract</p> <p>Background</p> <p>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, which rapidly leads to chronic respiratory failure requiring mechanical ventilation. Currently, forced vital capacity (FVC) < 50% is considered as physiologic mar...

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Bibliographic Details
Main Authors: Scoditti Cristina, Lacedonia Donato, Gadaleta Felice, Maniscalco Mauro, Cassano Anna, Spicuzza Lucia, Carratù Pierluigi, Boniello Ester, Di Maria Giuseppe, Resta Onofrio
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Orphanet Journal of Rare Diseases
Online Access:http://www.ojrd.com/content/4/1/10